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Article Navigation> JOURNAL OF BEIJING INSTITUTE OF TECHNOLOGY> 2009> 18(3): 327-332
ZHANG Jun, ZHOU Zhi-ming, XUE Wei-zhe, LI Zhi-huai. A Facile Synthesis of N-alkyl-4'-methyl-1,1'-biphenyl-2-sulfona-mide via Linking DoM Reaction with Suzuki Reaction[J]. JOURNAL OF BEIJING INSTITUTE OF TECHNOLOGY, 2009, 18(3): 327-332.
Citation: ZHANG Jun, ZHOU Zhi-ming, XUE Wei-zhe, LI Zhi-huai. A Facile Synthesis ofN-alkyl-4'-methyl-1,1'-biphenyl-2-sulfona-mide via Linking DoM Reaction with Suzuki Reaction[J].JOURNAL OF BEIJING INSTITUTE OF TECHNOLOGY, 2009, 18(3): 327-332.
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A Facile Synthesis ofN-alkyl-4'-methyl-1,1'-biphenyl-2-sulfona-mide via Linking DoM Reaction with Suzuki Reaction

  • Research and Development Center for Pharmaceuticals, School of Chemical Engineering and Environment, Beijing Institute of Technology, Beijing 100081, China

  • Received Date:2008-12-19
    Abstract
  • Six N-alkyl-4'-methyl-1,1'-biphenyl-2-sulfonamides were synthesized facilely and efficiently from low cost and readily available benzenesulfonyl chloride and C 1- C 4fatty amines via linking D oM reaction with Suzuki reaction. The structures of the new compounds synthesized were confirmed by elemental analysis,IR,1H NMR and MS. This new method makes a feature of low cost and readily available starting material, fewer steps, mild condition, easiness to operate and higher yield.
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